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强化阿托伐他汀治疗高血压并发阵发性房颤的相关性研究
引用本文:王玉霞,刘凤静,李学强. 强化阿托伐他汀治疗高血压并发阵发性房颤的相关性研究[J]. 中国现代医药杂志, 2011, 13(6): 37-39
作者姓名:王玉霞  刘凤静  李学强
作者单位:中国航天科工集团公司731医院,北京,100074
摘    要:目的观察探讨强化阿托伐他汀治疗对高血压并发阵发性房颤干预治疗的价值及对超敏C反应蛋白(highsensitivity Creaction protein,hsCRP)和低密度脂蛋白胆固醇(LDL-C)水平的影响。方法选择高血压并发阵发性房颤患者98例,随机分成治疗组和对照组,治疗组50例给予阿托伐他汀40mg/d口服,对照组48例给予常规治疗。入选时及治疗3、6、12个月后,检测两组患者hsCRP水平,记录房颤发作频度及持续时间。结果治疗后3个月、6个月时,两组阵发性房颤发生率比较差异无统计学意义(P>0.05),而治疗后12个月随访时,治疗组阵发性房颤发生率(14.9%)明显低于对照组(43.5%),两组间比较差异有统计学意义(P<0.05),治疗组hsCRP及LDL-C水平均显著低于对照组(P<0.05)。结论强化阿托伐他汀治疗可以减少高血压并发阵发性房颤的复发且具有较好的安全性。

关 键 词:阵发性房颤  高血压  阿托伐他汀  强化治疗

The association study of atorvastatin intensive treatment to hypertension with PAF
Wang Yuxia,Liu Fenging,Li Xueqiang. The association study of atorvastatin intensive treatment to hypertension with PAF[J]. Modern Medicine Journal of China, 2011, 13(6): 37-39
Authors:Wang Yuxia  Liu Fenging  Li Xueqiang
Affiliation:Wang Yuxia,Liu Fengjing,Li Xueqiang.731 Hospital of China Aerospace Science and Industry Corporation,Beijing 100074
Abstract:Objective To observe and explore the value of interference therapy of the atorvastatin intensive treatment to hypertension with PAF and the effect of hsCRP and the level of LDL-C.Methods All 98 hypertension with PAF patients choosing in random were divided into two groups:treatment group(50 cases) was taken orally 40mg/d and the control group(48 cases) was taken common treatment.After 3,6,12 months,evaluated the hCRP level of the two groups,recorded the frequencies of atrial fibrillation and the time durati...
Keywords:PAF Hypertension Atorvastatin Intensive treatment  
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