高血压中医证型与血脂、血尿酸关系研究

目的探讨高血压中医证型与血脂、血尿酸关系。方法收集高血压患者118例，进行中医辨证分型。另选同期健康体检者20例作对照组。检测两组总胆固醇（TC）、低密度脂蛋白胆固醇（LDL—C）、高密度脂蛋白胆固醇（HDL-C）、甘油三酯（TG）、血尿酸（SUA）。比较高血压各证型组及对照组血脂、血尿酸水平及异常率。结果高血压阴虚阳亢证和高血压痰湿壅盛证血脂、SUA异常者均高于对照组（P〈0．05）且SUA异常者低于高血压阴阳两虚证（P〈0．05）。阴虚阳亢证、痰湿壅盛证、肝火亢盛证TC高于对照组（P〈0．01）；痰湿壅盛证型的TG高于阴虚阳亢证型（P〈0．05）；高血压阴阳两虚证型的HDL．C低于对照组及高血压其他各证型（P〈0．05或〈0．01），高血压阴阳两虚证型SUA高于对照组其他组及高血压其他各证型对照组（P〈0．01）。结论高血压患者TG升高与痰湿壅盛证有关，可作为高血压痰湿壅盛证的参考指标。HDL—C下降、SUA升高与阴阳两虚有关，可作为阴阳两虚证的参考指标。．

Clinical research on the relationship of TCM Syndrome type and blood lipids, blood uric acid

Objective To study the relationship between blood lipids, blood uric acid and hypertension.Methods 118 patients with hypertension, the TCM Syndrome type were collected. 20 cases over the same period were selected as the healthy control group. The total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides ( TG ), serum uric acid (SUA) were detected. Blood lipids, blood uric acid levels and abnormal rate in various syndromes of hypertension group and control group were compared.Results Of hypertension and high blood pressure phlegm dampness Yinxuyangkang card lipids, SUA exception caught was higher(P ＜ 0.05) lower blood pressure and SUA abnormal deficiency of both yin and yang( P ＜ 0.05 ). Yin card,phlegm dampness card ,anger Kang Sheng card TC higher(P ＜0.01 ) ;phlegm dampness syndromes TG than hyperactivity syndrome(P ＜0.05) ;high deficiency of both yin and yang type of blood pressure,HDL-C lower than the control group and other syndromes of hypertension(P ＜0.05 or ＜0.01 ) deficiency of both yin and yang type of high blood pressure higher than other groups SUA and other syndromes of hypertension the control group ( P ＜ 0. 01 ).Conclusion In patients with hypertension,the elevated TG was corralated with the phlegm dampness,and the phlegm dampness could be used as evidence of high blood pressure reference. HDL-C decreased,SUA increased with the yin and yang,and it could be used as the reference to deficiency of both yin and yang.