兰州市区汉族、回族正常人群骨密度研究

目的 通过测量兰州市区1865例次汉族、回族健康人群的骨密度(bone mineral density,BMD),确定本地区汉族、回族BMD的正常参考值范围,并比较研究汉族、回族BMD随年龄变化的规律.方法 使用X线骨密度仪(prodigy DPX-NT型美国GE-Luner公司)测定兰州市区20～75岁以上的汉族、回族健康人群的腰椎和股骨BMD,按不同性别每5岁分为一年龄组,得出BMD均值、标准差.结果 汉族、回族男性及女性各部位出现骨峰值的年龄段略有不同,腰2～4椎体汉族、回族男性及女性基本在30～35岁左右达到骨峰值,汉族、回族男性及女性的股骨颈骨峰值在25～30岁年龄组,汉族、回族男性及女性的大转子骨峰值在20～25岁年龄组,汉族、回族男性及女性的Ward三角区骨峰值在25～30岁年龄组,但多数均在40岁前随骨量逐渐增加而达到骨峰值.其后随年龄的增长BMD降低,女性BMD在50岁后加速下降.男性无加速下降的趋势.结论 本研究建立了兰州市区汉族、回族各年龄段BMD的正常值参考范围,为今后骨质疏松的预防、诊断、研究提供了客观数据和比较的依据.

Study of bone mineral density of Han and Muslim nationality in normal people in Lanzhou

Objective To determine the normal reference range of bone mineral density（BMD） of Han and Muslim nationality of 1 865 people in health in Lanzhou and to investigate the change regularities of I3MD with age. Methods BMD values of lumbar spine and femur in healthy subjects were determined by BMD beam instrument （Model prodigy DPX NT made by GE-Luner Co. Ltd, America） in Lanzhou residents aged over 20-75 years. The mean BMD value,standard deviation（SD） were evaluated and age was put in one group per 5 years. Results The peak bone mass for each skeleton site appeared in different ages in both Han and Muslim nationality. The peak bone mass of lumbar vertebrae 2 to 4,femoral neck,great rotor and Ward triangle achieved their peak bone mass in 30 to 35 years group,25 to 30 years group,20 to 25 years group and 25 to 30 years group,respectively. But most of all achieved peak bone mass before the age of 40, and BMD decreased with the increase of age. The BMD in females showed a sharp decline after 50 years while no such a tendency occurred in males. Conclusion This study established the normal BMD of Han and Muslim nationality in Lanzhou. It may provide useful evidence and data for future osteoporosis research.