老年高血压人群代谢综合征患病分析

目的 分析不同性别老年高血压人群代谢综合征(MS)患病率及特点.方法 采用分层整群方法对武汉市武昌区社会福利院年龄≥65岁高血压患者2 136例,按不同年龄、不同高血压分级、血糖水平和血脂进行分组,分析各组不同性别老年人MS患病情况.结果 MS患病率随年龄增长而降低.女性患病率高于男性,65～75岁组、>75～85岁组和>85～95岁组男女MS患病率分别为28.8% vs 21.2%,22.3%vs 16.4%和17.8% vs 12.4%(均P<0.05);在高血压分级中MS患病率差异无统计学意义,但1级、2级和3级高血压MS患病率女性均高于男性,分别为23.2%vs15.0%,22.1%vs 16.4%和23.9%vs 16.6%(P<0.05或<0.01);随血糖升高,MS的患病率逐渐增加,女性患病率高于男性,空腹血糖(FPG)<6.1 mmol/L组、FPG≥6.1～7.0 mmol/L组和FPG>7.0 mmol/L组男女MS患病率为9.5%vs3.9%,42.7%vs 28.8%和66.O0%vs 50.3 %(P<0.05或P<0.01);高TG患病率最高.其次为低高密度脂蛋白胆固醇(HDL-C)、高低密度脂蛋白胆固醇(LDISC)和高总胆固醇(TC);在高甘油三酯(TG)、低HDL-C、高TC组中,女性患病率高于男性,分别为54.6%vs 43.2%、45.2%vs 36.2%和32.5%vs 23.1%(P<0.01),而在高HDL-C组中男性患病率高于女性,分别是41.9%"34.5%(P<0.05).结论 老年MS患病率随年龄增长而降低,随血糖的升高而增高.女性MS患病率明显高于男性,在高血压及血糖分层中女性患病率均高于男性.

Analysis on prevalence and characteristics of metabolic syndrome among old people with hypertension

Objective To analyze the prevalence and characteristics of metabolic syndrome（MS） between different sexes in the old people with hypertension. Methods Using cluster muhistratum sampling stratification according to age,hypertension grade,blood sugar and blood lipid,2 136 inhabitants with hypertension over 65 years old in Wuchang Region welfare homes of Wuhan city were divided into groups. The prevalence in different sexes of the old people in every group of MS was analyzed. Results The prevalence of MS decreased with increasing age and was higher in females than in males. At 65-75 years group, 75-85 years group and 〉85-95 years group,the prevalence of MS was higher in females than in males, respectively 28.8 % vs 21.2% ,22.3% vs 16.4% and 17.8% vs 12.4% （all P 〈0.05）. The prevalence of MS was no statistic significance in the hypertension grade. The prevalence of MS in grade 1 ,grade 2 and grade 3 of hypertension was higher in females than in males, respectively23.2% vs 15.0%,22.1% vs 16.4% and 23.9% vs 16.6%（P 0.05 or 〈0.01）. The prevalence of MS increased with increasing fasting plasma glucose（FPG） and was higher in females than in males in high FPG. At FPG〈6.1 mmol/L group,FPG〈6.1- 7.0 mmol/L group and FPG〉7.0 mmol/L group,the prevalence of MS was higher in females than in males, respectively 9.5 % vs 3.9 %, 42.7 % vs 28.8 % and 66.0 % vs 50.3 % （ P 〈0.05 or 〈0.01）. The prevalence of MS was the highest in high TG group,and the proper order was low HDL-C group,high LDL-C group and high TC group. At high TG group,low HDL-C group and high TC group, the prevalence of MS was higher in females than in males, respectively 54. 6% vs 43. 2%, 45. 2% vs 36.2% and 32. 5% vs 23.1%（ P 〈0. 01）. At high LDL-C group, the prevalence of MS was higher in males than in females, 41.9 % vs 34.5 % （ P 〈 0.05）. Conclusion The prevalence of MS among the old people decreased with increasing age, and increased with increasing FPG. The prevalence of MS was higher in females than in males, in females higher than in males in every grade of hypertension and FPG.