| 电针不同穴位对去卵巢大鼠HPO轴的影响 |
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| 引用本文： | 宫静,程凯,张露芬.电针不同穴位对去卵巢大鼠HPO轴的影响[J].中华中医药杂志,2011(3):595-597. |
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| 作者姓名： | 宫静 程凯 张露芬 |
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| 作者单位： | 北京中医药大学针灸推拿学院; |
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| 基金项目： | 教育部新世纪优秀人才支持计划资助课题(No.0100413); 国家中医药管理局针灸生物学三级实验室~~ |
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| 摘 要： | 目的:观察电针太溪(KI3)、三阴交(SP6)、关元(RN4)穴对去卵巢大鼠下丘脑-垂体-卵巢(HPO)轴的调节作用,探讨腧穴主治作用的特异性。方法:以3.5月龄去卵巢大鼠为更年期模型,选取太溪、关元、三阴交穴进行电针刺激,30d后测定雌二醇(E2)、卵泡刺激素(FSH)、促黄体生成素(LH)、促性腺激素释放激素(GnRH)的含量。结果:与正常组比较,模型组大鼠血清E2水平显著降低(P<0.01),FSH、LH、GnRH水平明显升高(P<0.01)。与模型组相比,各穴位组电针治疗后,E2水平显著升高(P<0.05);FSH、LH、GnRH水平明显降低(P<0.05),尤以电针三阴交组、电针关元组降低显著。结论:电针对去卵巢大鼠紊乱的HPO轴功能具有良性调节作用,且不同穴位具有特异性。
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| 关 键 词： | 更年期 去卵巢大鼠 HPO轴 太溪 三阴交 关元 腧穴特异性 |
Effects on hypothalamic-pituitary-ovarian axis by electroacupuncture at different points in ovariectomized rats |
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| GONG Jing,CHENG Kai,ZHANG Lu-fen.Effects on hypothalamic-pituitary-ovarian axis by electroacupuncture at different points in ovariectomized rats[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011(3):595-597. |
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| Authors: | GONG Jing CHENG Kai ZHANG Lu-fen |
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| Institution: | GONG Jing,CHENG Kai,ZHANG Lu-fen(College of Acupuncture and Moxibustion,Beijing University of Chinese Medicine,Beijing 100029,China) |
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| Abstract: | Objective: To observe the regulating action on Hypothalamic-pituitary-ovarian(HPO) Axis by electroacupuncture(EA) at Taixi(KI3),Sanyinjiao(SP6),Guanyuan(RN4) points in ovariectomized rats,and to explore the specific effects of different points.Methods: Ovariectomized SD Rats aged 3.5 months were chosen as climacteric model,treated by electroacupuncture at Taixi,Sanyinjiao,Guanyuan points respectively.30 days later,levels of estradiol(2E),follicle stimulating hormone(FSH),luteinizing hormone(LH) and gonadotr... |
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| Keywords: | Climacteric Ovariectomized rats HPO axis Taixi Sanyinjiao Guanyuan Point specificity |
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