小潮气量机械通气在小儿呼吸衰竭中的应用

目的探讨小潮气量机械通气的临床治疗及肺保护效果。方法选取48例呼吸衰竭患儿,原发疾病涉及严重感染、外伤和重大手术等。除综合治疗外,均采用小潮气量机械通气,观察上机前后的血气分析、呼吸机参数、机械通气相关并发症等指标。结果与大潮气量机械通气相比,小潮气量肺保护通气的呼吸性酸中毒纠正率与之无明显差异,而后者呼吸机相关性肺损伤(VILI)的发生率较前者有明显下降。结论小潮气量机械通气适用于儿童呼吸衰竭的治疗,有助于防止发生肺气肿、纵隔气肿或皮下气肿。

Application of Low Tidal Volume Ventilation in Children with Acute Respiratory Failure

Objective To study the therapeutic and protective effect of low tidal volume(LTV) ventilation in children with acute respiratory failure.Methods Forty-eight patients with respiratory failure were enrolled in our study.The patients were suffered from severe infection,trauma or after major operation.Besides general treatments,they were all given ventilation with LTV.Blood gas,ventilation parameters and complications related to ventilation were also measured.Results No significant difference was found between the patients with high tidal volume(HTV) and those with LTV in the results of improving respiratory acidosis.But the incidence of(ventilated-)induced lung injury(VILI) was lower in LTV patients.Conclusion LTV ventilation is preferable for children with acute respiratory failure and beneficial for alleviation of VILI.