我院259例药品不良反应报告分析

目的：分析探讨我院药品不良反应（ADR）发生的特点,为临床安全用药提高参考。方法：对我院2007-2012年收集到的259例ADR报告进行统计、分析。结果：259例ADR报告中,65岁以上老年患者ADR的发生率最高（40.15%）;以静脉滴注给药引发的最多（75.68%）;引发ADR的药物中抗菌药物品种和例数最多;ADR表现以皮肤及其附件损害最为常见（36.94%）;有38例ADR由药师直接上报。结论：ADR虽不可避免,但医、药、护、患要共同努力,加强ADR的报告和监测工作。在这项工作中,临床药师起到了越来越重要的作用。

Analysis of 259 Cases of Adverse Drug Reaction Reports in Our Hospital

OBJECTIVE： To investigate the characteristics of adverse drug reactions （ADR）occurred in our hospital to promote safe drug use in the clinic. METHODS： 259 cases of ADR reported in our hospital during 2007--2012 were analyzed statistically. RESULTS： Among 259 ADR cases, incidence of patients aged over 65 was high （40.15%）, and incidence of intravenous infusion was high （75.68%）. Among the drugs related to ADR, antimicrobial drugs had the largest proportion in the field of kinds and case number. The lesion of skin and appendents was the most common ADR manifestation （36.94%）. 38 ADR cases were reported directly by clinical pharmacists. CONCLUSIONS： Though ADR is inevitable, doctors, pharmacists, nurses as well as patients should make joint efforts to strengthen ADR reporting and monitoring. Clinical pharmacists have played an increasingly important role in this work.