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胎儿腮腺内瘦素和瘦素受体免疫组织化学观察
引用本文:伍雪芳,彭彦霄,柯红林,王惠珠,贾雪梅.胎儿腮腺内瘦素和瘦素受体免疫组织化学观察[J].安徽医科大学学报,2004,39(2):113-115.
作者姓名:伍雪芳  彭彦霄  柯红林  王惠珠  贾雪梅
作者单位:安徽医科大学组织学与胚胎学教研室,形态学中心实验室,合肥,230032
基金项目:安徽省教育厅自然科学基金
摘    要:目的观察胎儿腮腺内瘦素和瘦素受体的表达、分布及发育规律.方法 HE染色法和免疫组化SABC法.结果胎儿腮腺纹状管、小叶间导管上皮细胞呈瘦素及瘦素受体免疫反应阳性,免疫反应产物分布于导管上皮细胞胞质内,细胞核呈阴性反应.在胚胎发育的不同阶段,免疫反应强度亦不等.结论胎儿腮腺内有瘦素和瘦素受体表达,可能参与调节胎儿腮腺和胃肠的发育及功能活动.

关 键 词:蛋白质类  免疫组织化学  腮腺  胎儿
文章编号:1000-1492(2004)02-0113-03
修稿时间:2003年8月10日

Immunohistochemical observation of the leptin and its receptor in the parotid gland of human fetus
Wu Xuefang,Peng Yanxiao,Ke Honglin et al.Immunohistochemical observation of the leptin and its receptor in the parotid gland of human fetus[J].Acta Universitis Medicinalis Anhui,2004,39(2):113-115.
Authors:Wu Xuefang  Peng Yanxiao  Ke Honglin
Abstract:Objective To study the expression,distribution and development regularity of leptin and its receptor in the fetal parotid gland. Methods HE staining and immunohistochemical SABC methods were used. Results The epithelial cells of striated and interlobular ducts showed leptin and its receptor immunoreactivity. The immunocomplexes distributed in the epithelial cytoplasm of the ducts. Nuclei were negative. The immunoreactive intensity was unequal at different embryonic stages of fetal parotid gland. Conclusion Leptin and its receptor was present in fetal parotid gland, which may be involved in the fetal parotid gland and gastrointestinal development and the functional regulation.
Keywords:proteins  immunohistochemistry  parotid gland  fetus
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