| 镇痛灵对大鼠实验性糖尿病降血糖作用及机制的研究 |
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| 引用本文： | 陶惠然,苗乃全,付秀云,刘月霞,张桂芳. 镇痛灵对大鼠实验性糖尿病降血糖作用及机制的研究[J]. 中草药, 1996, 27(8): 475-478 |
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| 作者姓名： | 陶惠然 苗乃全 付秀云 刘月霞 张桂芳 |
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| 作者单位： | 牡丹江医学院!157011(陶惠然，苗乃全)，黑龙江省宾县医院(付秀云)，佳木斯医学院(刘月霞，张桂芳) |
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| 摘 要： | 中药剂制镇痛灵25g／kg腹腔注射12d，对正常大鼠和糖尿病大鼠均有降血糖作用。作用机制可能与其促进四氧嘧啶引起的大鼠胰岛β细胞损伤的修复和胰岛素的分泌，增加肝糖元合成，改善耐糖功能有关。
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| 关 键 词： | 镇痛灵 四氧嘧啶 糖尿病 |
| 收稿时间： | 1995-05-18 |
Studies on Hypoglycemic Action of Zhentongling in Experimental Diabetic Rats and Its Mechanism of Action |
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| Tao Huiran,Liu Yuexia. Studies on Hypoglycemic Action of Zhentongling in Experimental Diabetic Rats and Its Mechanism of Action[J]. Chinese Traditional and Herbal Drugs, 1996, 27(8): 475-478 |
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| Authors: | Tao Huiran Liu Yuexia |
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| Affiliation: | Mudanjiong Medical College, Mudanjiong;Mudanjiong Medical College, Mudanjiong;Mudanjiong Medical College, Mudanjiong |
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| Abstract: | Zhentongling(ZTL)25g/kg injected intraperitioneally for 12 days could decrease blood sugar levels of normal and diabetic rats induced by alloxan.Concentrations of serum insulin and hepatic glycogen were increased,and function of glucose tolerance improved.Histologic observation showed that ZTL could repair structure of pancreatic inlet β cells injured by alloxan. |
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