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Cytotoxic effect of low-density lipoproteins |
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| Authors: | Nagornev V A Voskan'yants A N Vinogradov A G Zhdanova O Yu Denisenko A D |
| Affiliation: | (1) Russian Academy of Medical Sciences, Research Institute of Experimental Medicine, St. Petersburg |
| Abstract: | The cytopathogenic effect of various modified lipoproteins on cultured peritoneal macrophages was studied in vitro. After minor peroxide modification lipoproteins induced apoptosis of macrophages. Immune complexes containing oxidized lipoproteins caused cell necrosis. |
| Keywords: | modified lipoproteins peritoneal macrophages apoptosis necrosis |
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