| 亚健康状态老年人血白细胞介素18和白细胞介素10水平变化及意义 |
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| 引用本文： | 王淑斐,许金成,程明刚. 亚健康状态老年人血白细胞介素18和白细胞介素10水平变化及意义[J]. 实用老年医学, 2011, 25(5): 388-389,392. DOI: 10.3969/j.issn.1003-9198.2011.05.011 |
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| 作者姓名： | 王淑斐 许金成 程明刚 |
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| 作者单位： | 南方医科大学附属深圳宝安人民医院体检中心,广东省深圳市,518101 |
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| 摘 要： | 目的探讨白细胞介素18（IL-18）、白细胞介素10（IL-10）在老年亚健康状态发生发展中的作用及相互关系。方法应用酶联免疫吸附法测定45例亚健康状态老年人（≥60岁）血浆IL-18和血清IL-10水平,以42例亚健康状态老年前期（50～59岁）和30例健康老年人（≥60岁）作比较,分析它们之间的关系。结果亚健康状态老年人血浆IL-18水平显著高于健康老年人（P〈0.01）,以及亚健康老年前期组（P〈0.05）,血清IL-10水平则显著低于对照组（P〈0.01）和老年前期组（P〈0.05）;血浆IL-18水平与血清IL-10水平之间呈负相关（r=-0.882,P〈0.01）。结论 IL-18和IL-10可能共同构成一局部网络,并可能参与亚健康状态的发生发展过程。
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| 关 键 词： | 亚健康 白细胞介素18 白细胞介素10 老年 |
Study on plasma interleukin 18 and serum interleukin 10 in elderly people with sub-health |
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| WANG Shu-fei,XU Jin-cheng,CHENG Ming-gang. Study on plasma interleukin 18 and serum interleukin 10 in elderly people with sub-health[J]. Practical Geriatrics, 2011, 25(5): 388-389,392. DOI: 10.3969/j.issn.1003-9198.2011.05.011 |
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| Authors: | WANG Shu-fei XU Jin-cheng CHENG Ming-gang |
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| Affiliation: | WANG Shu-fei,XU Jin-cheng,CHENG Ming-gang.Department of Body Examination,Affiliated Shenzhen Baoan Hospital of Nanfang Medical University,Shenzhen 518101,China. |
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| Abstract: | Objective To study the changes of plasma interleukin 18(IL-18) and serum interleukin 10(IL-10) in the elderly people with sub-health (SH) and the clinical significance.Methods The plasma level of IL-18 and serum level of IL-10 in 45 elderly people with SH were measured by enzyme linked immune sandwich assay (ELISA),42 prevenient elderly people with SH and 30 healthy elderly persons(HEP) were enrolled as control.The relationships of IL-18 and IL-10 with SH were analyzed.Results The level of IL-18 in elderly ... |
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| Keywords: | sub-health interlukin-18 interleukin-10 aged |
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