| 老年前列腺癌去势治疗对血清脂联素及颈动脉内膜-中层厚度的影响 |
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| 引用本文： | 周萍,富路,王秋军,高倩萍. 老年前列腺癌去势治疗对血清脂联素及颈动脉内膜-中层厚度的影响[J]. 实用老年医学, 2011, 25(5): 384-387. DOI: 10.3969/j.issn.1003-9198.2011.05.010 |
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| 作者姓名： | 周萍 富路 王秋军 高倩萍 |
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| 作者单位： | 1. 哈尔滨医科大学附属第二医院老年病科,黑龙江省哈尔滨市,150086
2. 哈尔滨医科大学附属第一医院心内三科,黑龙江省哈尔滨市,150001 |
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| 基金项目： | 哈尔滨市科技局资助项目，哈尔滨医科大学附属第二医院博士基金资助项目 |
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| 摘 要： | 目的探讨老年前列腺癌去势治疗对血清脂联素及颈动脉内膜中层厚度（IMT）的影响。方法 32例老年前列腺癌去势患者（CAS组）,32例单纯前列腺切除患者（PH组）,30例年龄匹配的对照组（CON组）,分别检测IMT、腰臀比（EHR）、总睾酮（TT）、游离睾酮（FT）、一氧化氮（NO）、内皮素（ET-1）及脂联素。结果去势组与对照组比较,TT、FT、脂联素水平降低,WHR显著增高,IMT增厚;IMT与FT负相关（r=-0.382,P=0.04）、脂联素与FT正相关（r=0.535,P=0.033）。结论内源性睾酮缺失是动脉粥样硬化的危险因素之一。
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| 关 键 词： | 睾酮 脂联素 内膜中层厚度 前列腺癌 老年人 |
Effects of castration on serum adiponectin and carotid artery intima-media thickness in patients with prostatecancer |
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| ZHOU Ping,WANG Qiu-jun,FU Lu,GAO Qian-ping. Effects of castration on serum adiponectin and carotid artery intima-media thickness in patients with prostatecancer[J]. Practical Geriatrics, 2011, 25(5): 384-387. DOI: 10.3969/j.issn.1003-9198.2011.05.010 |
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| Authors: | ZHOU Ping WANG Qiu-jun FU Lu GAO Qian-ping |
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| Affiliation: | ZHOU Ping,WANG Qiu-jun.Department of Geriatrics,the Second Affiliated Hospital of Harbin Medical University,Harbin 150086,China,FU Lu,GAO Qian-ping.Depatment of Cardiovascular,the First Affiliated Hospital of Harbin Medical University,Harbin 150001 |
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| Abstract: | Objective To explore the effects of castration on level of adiponitrile and carotid artery intima-media thickness (IMT)in patients with prostate cancer.Methods Thirty-two old patients with prostate cancer received castration were recruited (CAS),32 patiets received focal prostatectomy and 30 age-matched healthy control group.IMT,waist-hip ratio(WHR) and total testosterone(TT),free testosterone (FT),nitric oxide(NO),endothelin-1(ET-1)and adiponitrile were tested.Results In CAS group,TT and FT were decreased ... |
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| Keywords: | testosterone adiponitrile IMT prostate cancer aged |
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