煤矿工人胃部有关疾病与Hpylori感染及相关因素的调查

目的:了解煤矿工人胃部有关疾病的患病情况,探讨煤矿工人胃部有关疾病与Hpylori感染及相关因素关系.方法:用分层随机整群抽样方法选取340名煤矿工人进行问卷调查.采用细菌培养法和ELISA法检测Hpylori感染;疾病诊断按胃镜及病理学规定标准进行;资料分析采用X~2检验,Logistic回归分析等.结果:煤矿工人胃部有关疾病的患病率为77.8%,其中井下工人的患病率为80.7%,井上工人的为68.5%;Hpylori感染者的胃部有关疾病的患病率为85.0%,非感染者的患病率为58.6%;饮酒者胃部有关疾病的患病率为79.5%,非饮酒者的患病率为66.7%.结论:煤矿工人胃部有关疾病发病的危险因素主要是饮酒和Hpylori感染,井下工人特有的职业危险因素为粉尘暴露.

A cross-sectional study on the relationship among H pylori infection,some risk factors and gastroduodenal diseases in coal miners

AIM:To search for the risk factors that influences the prevalence rate of gastroduodenal diseases in coal miners,and to seek protection for the health of coal miners. METHODS:A total of 340 coal miners from three coalmines were chosen by the method of stratified random cluster sampling.Face to face interview was conducted to fill the unified questionaire.Gastroendoscopy were performed in 306 subjects to detect the situation of gastro- duodenal diseases according to Sydney system of diagnosis.At the same time,mucosal biopsies were taken according to the regulated location for H pylori culture and pathological examina- tion.Blood samples were obtained to detect the anti-H pylori U-IgG by enzyme-linked immuno- sorbent assay(ELISA). RESULTS:The prevalence rate of gastroduo- denal diseases in coal miners was 77.8%(68.5% in ground coal miners,80.7% in underground miners).The prevalence rate of gastroduodenal diseases was 85.0% in coal miners with H pylori infection,and 58.6% in those without H pylori infection;it was 79.5% in coal miners who drank alcohol and 66.7% in those who didn't drink. CONCLUSION:Alcohol-drinking,career,and H pylori infection were risk factors of gastroduode- hal diseases,and dust exposure was also a risk factor in underground coal miners.