重型颅脑损伤并发高钠血症35例临床研究

目的探讨重型颅脑损伤伴高钠血症的病凶和发病机制及对预后的影响。方法回顾分析35例重症颅脑损伤伴高钠血症患者临床资料。结果重症颅脑损伤伴高钠血症的患者死亡率大67．68％，发病率为8．59％。发生高钠血症的时间为1周之内，颅脑损伤后72h内出现的12例，死亡9例，24h内出现的高钠血症主要与原发性下丘脑损伤有关，而24h后出现的与下丘脑损伤和使用脱水剂有关。结论重症颅脑损伤出现高钠血症病死率高，且血钠值越高，病死率越高。

Clinical analysis of 35 cases severe craniocerebral injury camplicated hypernatremia

Objective To investigate the causes and mechanism of hypematremia and its prognosis in patients with severe craniocerebral injury. Methods The clinical data of 35 severe craniocerebral injury patients with hypematremia was analyzed retrospectively. Results Mortality rate of severe craniocerebral injury patients with Hypernatremia reach 67.68% , the disease incidence rate was 8.59%. All patients＇ hypematremia occurred in one week after craniocerebral injry, 12 cases occurred in 72hours and 9 patients died. In first 24 hours, the hypernatremia was correlated with primary hypothalamus injury, 24hours later, there was also correlated with the use of dehydration. Conclusion Severe cranioeerebral injury patients with hypernatremia have high mortality, the higher level natremia is, the higher mortality patients have.