Effect of antipsychotic and other classes of drugs on spontaneous locomotor activity and neurotoxicity in mice. |
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| Authors: | J R McLean R B Parker L L Coughenour |
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| Affiliation: | Department of Pharmacology, Warner-Lambert/Parke-Davis Pharmaceutical Research Division 2800 Plymouth Road, Ann Arbor, MI 48106, USA |
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| Abstract: | Quantitative estimates were made of the effects of several classes of drugs on spontaneous activity and neurotoxicity in mice. Clinically effective antipsychotic agents had a more selective action on spontaneous activity than other classes of drugs with the exception of clonidine and a related compound. |
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| Keywords: | Antipsychotics Locomotor activity Neurotoxicity |
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