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Automatic recognition and analysis of synapses. |
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| Authors: | J A Ungerleider R S Ledley F E Bloom |
| Institution: | National Biomedical Research Foundation, Georgetown University Medical Center, 3900 Reservoir Road, N.W., Washington D.C., USA;Laboratory of Neuropharmacology, Division of Special Mental Health Research, National Institutes of Mental Health, St. Elizabeth''s Hospital, Washington D.C., USA |
| Abstract: | An automatic system for recognizing synaptic junctions would allow analysis of large samples of tissue for the possible classification of specific well-defined sets of synapses based upon structural morphometric indices. In this paper the three steps of our system are described: (a) cytochemical tissue preparation to allow easy recognition of the synaptic junctions; (b) transmitting the tissue information to a computer; and (c) analyzing each field to recognize the synapses and make measurements on them. |
| Keywords: | Synaptic junctions Automatic recognition Cytochemical tissue preparation Morphology MACDAC FIDAC |
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