异叶梁王茶化学成分的研究

从异叶梁王茶Nothopanax davidii(Franch)Harms]树皮中分离得到两种五环三萜皂甙,经化学和光谱(IR,¹HNMR,¹³CNMR,¹H-¹H COSY,¹H-¹³C COSY,NOESY,MS)分析,分别鉴定为3-O-α-(3′,4′-O-二乙酰基)-L-吡喃阿拉伯糖-β-羟齐墩果-12-烯-28,29-双羧酸-28-O-α-L-吡喃鼠李糖(1→6)-β-D-吡喃葡萄糖(1→4)-β-D-吡喃葡萄糖]酯甙(Ⅱ)和3-O-α-(3′-O-乙酰基)-L-吡喃阿拉伯糖-3β-羟齐墩果-12-烯-28,29-双羧酸甙(Ⅱ),前者命名为异叶梁王茶甙Ⅰ,后者命名为异叶梁王茶甙Ⅱ。这两个皂甙均系新化合物。

STUDY ON THE CHEMICAL COMPONENTS FROM THE BARK OF NOTHOPANAX DAVIDII (FRANCH) HARMS

Two new oleanane type triterpene glycosides, named yiyeliangwanoside I and yiyeliangwanoside II, were isolated from Nothopanax davidii (Franch) Harms (Araliaceae). Their chemical structures were elucidated by means of chemical and spectrometric analysis. Yiyeliangwanoside I: C57H88O25, a white powder, mp 203-205 degrees C (dec.), alpha]D20-3.47(c 0.1, CH3OH). Its structure was determined as 3-O-alpha-(3',4'-O-dioic-acetyl)-L-arabinopyranosyl-3 beta-hydroxyolean-12-ene-28,29-dioic acid-28-O-alpha-L-rhamnopyranosyl-(1----6)-beta-D-glycopyranosyl- (1----4)-beta-D-glycopyranosyl] ester. Yiyeliangwanoside II: C37H56O10, a white powder, mp 240-244 degrees C (dec.), alpha]D20+36.5(c 0.1, CH3OH). Its structure was determined as 3-O-alpha-(3'-O-acetyl)-L-arabinopyranosyl-3 beta-hydroxyolean-12-ene-28,29-dioic acid.