13例肾癌病人介入治疗的临床分析

目的:观察肾癌肾动脉介入治疗的疗效及毒副反应。方法:2002年6月~2005年12月对13例不愿意接受手术或不能手术患者行肾动脉介入治疗,肾动脉内先注入化疗药物ADM40~60mg,MMC6~16mg,PDD40~60mg,然后注入无水酒精加碘油(1:1)10~20ml,最后用明胶海棉栓塞动脉主干,一个月做一次,2次结束后评价疗效。结果:13例病人治疗后,临床症状平均缓解率为90.32%,近期有效率为76.92%。毒副反应主要表现为腰痛加剧、发热、恶心、呕吐,经对症处理后,大部分于1周内,最长2周内缓解。结论:肾动脉灌注栓塞化疗是治疗不能手术肾癌的一疗效肯定,毒副反应可耐受的方法,值得临床推广应用。

Clinical research of interventional treatment for 13 patients with kidney cancer

Objective: To observe curative effect and side effect of interventional treatment of the kidney artery for patients with kidney cancer.Methods: From June 2002 to December 2005,13 patients who wouldn't like to be operated or can't accept operation were treated with interventional treatment of the kidney artery,Chemotherapy medicine: ADM40~60mg,MMC6~16mg and PDD40~60mg was injected in Kidney artery then absolute alcohol and lipiodot all together10~20ml(1:1) was injected;finally,use glutin sponge embolism to fill in the artery trunk.Once a month,the effect was evaluated twice later.Results: After the treatment,the average relief rate of clinical symptoms of the 13 patients was 90.20%,and recent efficiency rate was 76.92%.The side effect included: lumbago,fever,queasiness and vomit.But after treating,most symptoms relieved in one or two weeks.Conclusion: The chemotherapy priming embolism into kidney artery is an effective method,side effect is acceptable to treat kidney cancer who can not be operated.