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The relation between plasma tyrosine concentration and fatigue in primary biliary cirrhosis and primary sclerosing cholangitis
Authors:Pieter?CJ?ter Borg  author-information"  >  author-information__contact u-icon-before"  >  mailto:pterborg@zonnet.nl"   title="  pterborg@zonnet.nl"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Durk?Fekkes,Jan?Maarten?Vrolijk,Henk?R?van Buuren
Affiliation:(1) Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands;(2) Departments of Psychiatry and Neuroscience, Erasmus MC, Rotterdam, The Netherlands
Abstract:

Background  

In primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) fatigue is a major clinical problem. Abnormal amino acid (AA) patterns have been implicated in the development of fatigue in several non-hepatological conditions but for PBC and PSC no data are available. This study aimed to identify abnormalities in AA patterns and to define their relation with fatigue.
Keywords:
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