泌尿生殖道解脲和人型支原体感染及药敏分析

目的了解本地区泌尿生殖道支原体感染状况及药敏分析,指导临床合理用药.方法用液体培养的方法分离鉴定解脲支原体和人型支原体并做计数和9种药敏试验.结果3295例患者支原体培养阳性1033例,占31.4%;其中单纯UU 856例,占26%;单纯MH 20例,占0.61%;UU MH混合感染157例,占4.8%.泌尿生殖道支原体感染以UU为主,占83.4%;其次为MH占2.0%和UU MH占15.2%.药敏结果显示UU、MH和UU MH感染三种模式,均对强力霉素、米诺环素的敏感性强(74-90%),对罗红霉素的敏感性最差(0-7.5%);除UU对克拉霉素的敏感性为82%,对其余大环内脂类抗生素敏感性均小于50%以下.结论米诺环素、强力霉素可以作为目前治疗UU、MH和UU MH感染的首选.支原体耐药性的长期监测是指导临床治疗的重要依据,临床医生应根据药敏结果合理选择抗生素.

Analysis of Infection with Ureaplasma urealyticum and Mycoplasma hominis and antibiotic susceptibility

Objective To investigate the status of urogenital tract mycoplasma infections and the condition of antibiotic susceptibility in our area. Mathods Mycopiasma culture, identification and drug sensitivity test were used by liquid culture medium. The antibiotic include Azithromycin, clafithromycin, Josamycin, Roxithromycin, Doxycycliae, Minocycline, Levofloxacin, Ofloxacin and Spa. Results There are1033cases that infection with Mycoplasma in 3295 cases, the total infected rate was 31.4%o The simple infection with Ureaplasma urealyticum was 856 cases and the rate was 26%. Mycoplasma hominis was 20 cases and the rate was 0.61%.The mixed infection was 157 cases and the rate was 4.8%.Mycoplasma were high susceptible to Minecycline and Doxycycline and was low susceptible to Roxithromyein.The scnsitivtity of the Clarithromycin was 82% in Ureaplasma ureaiytieum. Conclusions Minecycline and Doxycyclinc will be selected firstly to clinical infection with Ureaplasma urealyticum,Mycoplasma hominis and mixed infection this finding also indicated resistance monitoring for clinical practices.