静脉注射丙种球蛋白佐治小儿病毒性脑炎疗效分析

目的:观察静脉注射丙种球蛋白(IVIG)佐治小儿急性病毒性脑炎的临床效果。方法:治疗组40例在常规治疗基础上,加用静脉注射丙种球蛋白,并与对照组46例疗效比较。结果:治疗组退热时间、止惊时间、神志开始恢复时间、神经系统病理反射消失时间及脑电图恢复正常时间较对照组明显缩短(P<0.01),两组颅神经损害开始恢复时间无显著差异(P>0.05)。结论:静脉注射丙种球蛋白佐治病毒性脑炎,能减轻脑组织损伤,临床疗效好。

Effect of immunoglobulin on acute viral encephalitis of children

Objective: To evaluate the efficacy of immunoglobulin in treatment of acute viral encephalitis of children. Methods: All 86 children who were suffered from acute viral encephalitis were received conventional treatment. At the same time, study group ( n = 40) were also treated with intravenous immunoglobulin and the therapeutic effect is compared with that of the control group ( n = 46) . Results: The time taken to bring down a fever, to stop spasm, to regain consciousness, to discontinue pathologic reflex and to discontinue abnormality in EEG of the study group was shorter than the of the control group, which showed significant difference ( P < 0. 01). No difference is found in the time to discontinue brain nerve damage between the two groups (P > 0. 05) . Conclusion: This study indicats that intravenous immunoglobulin can relieve brain tissue damage and is seffective in treating acute viral encephalitis of children .