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舒芬太尼复合甲磺酸罗哌卡因用于妇科术后硬膜外镇痛的观察
引用本文:李利华.舒芬太尼复合甲磺酸罗哌卡因用于妇科术后硬膜外镇痛的观察[J].华夏医学,2011,24(6):663-666.
作者姓名:李利华
作者单位:梧州市红十字会医院麻醉科,广西梧州,543000
摘    要:目的:观察舒芬太尼复合甲磺酸罗哌卡因或左旋布比卡因用于妇科术后硬膜外镇痛的效果.方法:选择56例ASA Ⅰ~Ⅲ级行妇科手术后需进行术后硬膜外镇痛的患者,随机分成2组,R组(n=28):舒芬太尼2μg/kg+甲磺酸罗哌卡因178 mg+氟哌利多2 mg;B组(n=28):舒芬太尼2μg/kg+左布比卡因125 mg+氟哌...

关 键 词:舒芬太尼  甲磺酸罗哌卡因  左旋布比卡因  术后镇痛

Observation of the epidural analgesia effect of sufentanyi combined with ropivacaine mesylate on patients after gynaecological surgery
LI Li-hua.Observation of the epidural analgesia effect of sufentanyi combined with ropivacaine mesylate on patients after gynaecological surgery[J].Acta Medicinae Sinica,2011,24(6):663-666.
Authors:LI Li-hua
Institution:LI Li-hua Dept.of Anesthesiology,Wuzhou Red Cross Hospital,Wuzhou 54300,China
Abstract:Objective: To observe the epidural analgesia effect of sufentanyl combined with ropivacaine mesylate or levobupivacaine on patients after gynaecological surgery.Methods: 56 ASA I-III patients who underwent postoperative epidural analgesia after gynecological surgery were randomly divided into two groups,group R and B.Patients in group R(n=28) were treated with sufentanil(2 μg Kg),ropivacaine mesylate(178 mg) and droperidol(2 mg);while patients in group B(n=28) were with sufentanil(2 μg Kg),levobupivacaine(125 mg) and droperidol(2 mg),all were added 0.9% NS to 100 ml,then they were injected into a one-time analgesia pump.Both groups were infused in LCP mode.Patients were given ropivacaine mesylate 29.8 mg as the loading dose before connecting with the pump analgesia,background dose of 2 ml h,and the lock time was 15 min.MAP,HR,RR,SpO2,VAS scores,anal flatus time,time of Bromage grading back to zero,nausea or vomit,hypotension,respiratory suppression and other adverse reactions of the patients were observed and recorded 6 h,12 h,24 h and 48h respectively after surgery.Results: There was of statistical difference between the postoperative pain scores of 4 measurements(P<0.05),while no statistical difference between the two groups in analgesic score(P>0.05),and no significant difference in postoperative SpO2,HR,MAP,RR,anal flatus time,nausea,vomiting and hypotension,either(P>0.05).There was of statistical difference in Bromage grading recovery time of zero(P<0.05).Conclusion: The epidural analgesia effect of sufentanil combined with 0.178% ropivacaine mesylate after gynecological surgery is satisfactory,with the advantages of motion block lighter,faster muscle recovery,fewer adverse reactions.Therefore,it should be introduced and widely applied.
Keywords:sufentanil  ropivacaine mesylate  levobupivacaine  postoperative epidural analgesia
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