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口腔细菌致牙釉质龋的病理学研究
引用本文:周学东,岳松龄,谭红. 口腔细菌致牙釉质龋的病理学研究[J]. 四川大学学报(医学版), 1994, 0(2)
作者姓名:周学东  岳松龄  谭红
作者单位:口腔医学院口腔内科学教研室
摘    要:作者利用细菌培养技术,在离体牙上产生早期牙釉质龋样损害,通过偏光显微镜和扫描电镜对龋损进行了病理学研究。结果表明,该技术能真实地模拟龋病的发生过程,其破坏方式和病理改变与自然龋损极为相似。观察发现,在龋损过程中,牙釉质表层的相对完整层的超微结构已经发生改变,表层釉质中的釉柱破坏、溶解产生小孔隙,这可能是龋损深入的重要途径。

关 键 词:口腔细菌,人工龋,病理研究

Pathological Study of Enamel Caries Produced by Oral Bacteria in Vitro
Zhou Xuedong , Yue Songling , Tan Hong. Pathological Study of Enamel Caries Produced by Oral Bacteria in Vitro[J]. Journal of Sichuan University. Medical science edition, 1994, 0(2)
Authors:Zhou Xuedong    Yue Songling    Tan Hong
Affiliation:Zhou Xuedong , Yue Songling , Tan Hong Department of Oral Medicine,College of Stomatology
Abstract:The authors used the bacterical culturemethod to study early enamel caries-like lesions in vit-ro. Pathologic changes in the lesions were observedunder polarized light microscope and scanning electronmicroscope. The results showed that this methodcould simulate the destructive procedures in cariousdevelopment.The destructive way and pathologicchanges of the caries-like lesions were very similar tothose of natural enamel caries. Under microscope ,theultrastructures of the relatively intact layer of theenamel surfaces were already changed.The prisms in1he enamel surfaces were destroyed,and dissolved toform small pores. The pores could be an importantpath of the carious development.
Keywords:Oral bacteria Artificial carious lesion Pathological study
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