EFFECT OF AGE ON THE SENSITIVITY OF UPPER AIRWAY REFLEXES |
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| Authors: | ERSKINE, R. J. MURPHY, P. J. LANGTON, J. A. SMITH, G. |
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| Affiliation: | University Department of Anaesthesia, Leicester Royal Infirmary Leicester LEI 5WW |
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| Abstract: | We have recorded the threshold concentration of inhaled ammoniavapour required to elicit reflex glottic closure (NH3TR) in102 healthy, nonsmoking volunteers (39 female) aged 17-96 yrin order to assess the effect of age upon upper airway reflexsensitivity. A single measurement of sensitivity was made ineach subject using a system delivering small concentrationsof ammonia vapour for single intermittent breaths to the upperairway and recording glottic closure using an inspiratory pneumotachograph.We found a strong positive correlation between age and NH3TR,indicating a decrease in upper airway reflex sensitivity withincreasing age. (Br. J. Anaesth. 1993; 70: 574575) |
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