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| 应用磁共振成像技术实时监测小鼠瘤体的初步实验研究 | |
| 引用本文： | 孙建军,廖联明,叶巽,潘国兵,帅海涛,陈自谦.应用磁共振成像技术实时监测小鼠瘤体的初步实验研究[J].医学研究杂志,2011,40(6):105-107. |
| 作者姓名： | 孙建军 廖联明 叶巽 潘国兵 帅海涛 陈自谦 |
| 作者单位： | 1. 南京军区福州总医院四七六临床部,福州,350002 2. 福建中医药大学中西医结合研究院,福州,350108 3. 南京军区福州总医院影像中心,福州,350025 |
| 摘 要： | 目的探讨采用临床型1.5T磁共振成像仪对小鼠瘤体进行非创伤性实时监测的方法。方法通过常规MRI轴位FSE序列T2加权成像、轴位SE序列T1加权成像和轴位、矢状位增强扫描成像,对瘤体进行观察,并于解剖和组化结果进行对比。结果通过优化成像参数,结果表明通过临床型的MRI可以对小鼠接种的肿瘤进行实时观察。成像结果和解剖所见完全吻合。结论通过常规的临床型MRI即可对小动物瘤体进行非创伤性观测,而无需采用动物专用型MRI。 |
| 关 键 词： | 磁共振成像 监测 肿瘤模型 |
| 收稿时间： | 2010/11/3 0:00:00 |
| 修稿时间： | 2011/4/20 0:00:00 |
The Initial Application of Magnetic Resonance Imaging in Mouse Model of Hepatocellular Carcinoma Monitoring |
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| Sun Jianjun,Liao Lianming,Ye Xing,Pan Guobing,Shuai Haitao,Chen Ziqian.The Initial Application of Magnetic Resonance Imaging in Mouse Model of Hepatocellular Carcinoma Monitoring[J].Journal of Medical Research,2011,40(6):105-107. | |
| Authors: | Sun Jianjun Liao Lianming Ye Xing Pan Guobing Shuai Haitao Chen Ziqian |
| Institution: | Sun Jianjun,Liao Lianming,Ye Xing,Pan Guobing,Shuai Haitao,Chen Ziqian.Radiologcal Department,the 476th Clinic Section of Fuzhou General Hospital of the PLA,Fujian 350002,China |
| Abstract: | Objective To establish a protocol for the non-invasive analysis of hepatocarcinogenesis in mice using a clinical 1.5 Tesla Magnetic Resonance Imaging scanner.Methods The scans of the murine tumor included axial T2-weighted FSE images,axial T1-weighted SE images and contrast enhanced images.Application of contrast agent was performed via tail vein.Results Through technical adaptation and optimization,we could detect murine tumors and provided histopathological evidence.These MR findings corresponded to hepat... |
| Keywords: | MRI Monitor Tumor model |
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