| 颅脑伤时生长抑素mRNA表达及电针对其影响 |
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| 引用本文： | 刘平,张留宝,苏志达,骆云,郭建.颅脑伤时生长抑素mRNA表达及电针对其影响[J].解剖学杂志,2003,26(4):364-368. |
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| 作者姓名： | 刘平 张留宝 苏志达 骆云 郭建 |
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| 作者单位： | 1. 第二军医大学南京军医学院组织学与胚胎学教研室,南京,210099
2. 南京林业大学动物学教研室 |
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| 基金项目： | 江苏省自然科学基金课题 (K9845) |
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| 摘 要： | 目的：探讨电针对颅脑伤的作用机理。方法：采用原位杂交组织化学技术，观察了实验性颅脑伤大鼠脑内生长抑素(SS)变化，并观察了电针治疗颅脑伤时对SS mRNA表达的作用。结果：电针可增加下丘脑室周核SS mRNA表达，而在海马则降低SS mRNA表达。结论：颅脑伤时，电针与SS可能在缓解疼痛方面起协同效应，并且电针可能对海马神经元起保护作用。
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| 关 键 词： | 颅脑伤 生长抑素 mRNA 表达 电针 |
Effects of electron-acupuncture on somatostatin mRNA expression in rat brain after head injury |
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| LIU Ping,ZHANG Liu-Bao,SU Zhi-Da,LUO Yun,GUO Jian.Effects of electron-acupuncture on somatostatin mRNA expression in rat brain after head injury[J].Chinese Journal of Anatomy,2003,26(4):364-368. |
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| Authors: | LIU Ping ZHANG Liu-Bao SU Zhi-Da LUO Yun GUO Jian |
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| Abstract: | Objective : To approach the mechanism of electron-acupunture in treatment of head injury. Methods : So-matostatin mRNA in situ hybridization was used to observe the changes in the rats brain after injury and the effect of electron-acupuncture on somatostatin mRNA expression. Results : Electron-acupuncture increased somatostatin mRNA expression in the hypothalamic paraventricular nucleus, but reduced it in the hippocampal neurons. Conclusion : Electron-acupuncture and somatostatin may help to ease pain and protect hippocampal neurons in brain damage. |
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| Keywords: | head injury somatostatin(SS) in situ hybridization electron-acupuncture rat |
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