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产妇及其新生儿血浆长链脂肪酸组成分析
引用本文:李红娟, 刘德华. 产妇及其新生儿血浆长链脂肪酸组成分析[J]. 中国公共卫生, 2001, 17(1): 6-7. DOI: 10.11847/zgggws2001-17-01-05
作者姓名:李红娟  刘德华
作者单位:1.山西医科大学儿少卫生教研室 太原030001
基金项目:经费来自山西省自然科学基金
摘    要:目的 分析了20名正常产妇静脉血及其新生儿脐血血浆中脂肪酸组成.方法 采用气相色谱法.结果 脐血中廿二碳六烯酸(DHA)、花生四烯酸(AA)含量显着高于母血(P<0.001);脐血中亚油酸(LA)含量为母血的1/5,而α亚麻酸(αLNA)含量脐血与母血无显着差异;脐血中DHA含量与母血中DHA含量高相关(r2=0.76,P<0.001),脐血中AA与母血中AA、LA含量均显着性相关(P<0.05,P<0.001).结论 母血中DHA、AA可优先通过胎盘满足胎儿需要;胎儿对n-3和n-6脂肪酸的利用可能存在差异.

关 键 词:廿二碳六烯酸  花生四烯酸
文章编号:1001-0580(2001)01-0006-02
收稿时间:1999-02-01
修稿时间:1999-02-01

Analysis of Long-Chain Fatty Acids Composition of Maternal and Neonatal Plasma.
LI Hong-juan, LIU De-hua. Analysis of Long Chain Fatty Acids Composition of Maternal and Neonatal Plasma.[J]. Chinese Journal of Public Health, 2001, 17(1): 6-7. DOI: 10.11847/zgggws2001-17-01-05
Authors:LI Hong-juan  LIU De-hua
Affiliation:1.Department of Child and Adolescent Health, Shan Xi Medical University Tai Yuan 030001
Abstract:Objective This study analysed plasmal long-chain fatty acids composition of 20 healthy.Method Normal perinatal maternal blood(M)and their umbilical cord blood(U)by gasliquid chromatography.Results Arachidonic acid(AA)and do cosahexaenoic acid(DHA)contents of U were significantly higher than M (P<0.001);DHA was highly related to DHA level of M(r2=0.76,P<0.001);AA content of U was related to AA and linoleic acid(LA)level of M(P<0.05,P<0.001).Conclusions The developong fetus migtht be preferentially supplied with DHA via the placenta;The usage of n-3 and n-6 fatty acid in fetus might be different.
Keywords:docosahexaenoic acid(DHA)  arachidonic acid(AA)
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