可逆性后部白质脑病综合征

可逆性后部白质脑病综合征(RPLS)是一组由多种原因引起的以神经系统异常为主要表现的综合征,临床表现以迅速进展的颅高压症状、癫发作、视觉障碍、意识障碍、精神异常为特征,神经影像学上显示以双侧大脑后部白质为主的水肿区,经及时有效治疗后临床表现和神经影像学改变可以完全恢复,一般不遗留有神经系统后遗症。核磁共振新技术的发展,突出显示了血管源性水肿的特点,有助于RPLS的正确诊断。

Reversible Posterior Leukoencephalopathy Syndrome

Reversible posterior leukoencephalopathy syndrome (RPLS) is a clinical entity caused by several reasons, and charactered by neurological alterations. Clinical findings include improving symptoms of intracranial hypertension, seizure, visual disturbance, confusion and altered mental status, and neuroradiologic findings show edema predominantly in the posterior cerebral white matter bilaterally. The clinical setting and neuroradiologic alterations can restore completely by treatment promptly and effectively, and generally there is no sequela of nervous system. More recent advances in MRI technology highlight the features of vasogenic edema, and conduce to accurate diagnosis of RPLS.