焦虑和抑郁障碍共病的脑电地形图研究

目的 本研究主要探讨焦虑和抑郁障碍共病的电生理学的特征。方法 按DSM-IV诊断标准收集25例焦虑和抑郁障碍共病患者(共病组)、30例抑郁症患者(抑郁组)、14例广泛性焦虑障碍和6例惊恐障碍患者(焦虑组)。对所有病例作脑电地形图检查。结果 尽管共病组、抑郁组和焦虑组的α功率值和右/左α功率比差异无显著性(P＞0．05)，但与正常对照组相比，三组均具有各自的特征；三组患者各脑区α频带绝对功率值与两量表分值间均无显著相关性(P＞0．05)。结论 焦虑和抑郁障碍共病患者无独特的脑电地形图特征。

A controlled study of brain electricity area mapping in comorbid anxiety and depression

Objective To explore the electrophysiological characteristics of patients with comorbid anxiety and depression(CAD). Methods 25 patients who both met major depression and generalized anxiety disorder(or panic disorder) in DSM IV( CAD group), 30 patients who only met major depression in DSM IV( depression group), 14 patients who only met generalized anxiety disorder and 6 patients who only met panic disorder in DSM IV(anxiety group) were investigated. All patients were examined brain by electricity area mapping(BEAM). Results There were no significantly differences among three groups in alpha power and right/left asymmetries, but they had different features compared with normal controls. Conclusion CAD had not unique characteristics of brain electricity area mapping.