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Activity of tigecycline (GAR-936), a novel glycylcycline,against Enterococci in the mouse peritonitis model
Authors:Nannini Esteban C  Pai Suresh R  Singh Kavindra V  Murray Barbara E
Institution:Center for the Study of Emerging and Re-Emerging Pathogens, Division of Infectious Diseases, Department of Internal Medicine, The University of Texas Medical School, Houston, Texas, USA. bem.asst@uth.tmc.edu
Abstract:A novel glycylcycline agent, tigecycline (GAR-936), was evaluated in vivo in the mouse model of peritonitis against three Enterococcus faecalis and four Enterococcus faecium isolates with different susceptibilities to vancomycin and tetracyclines, all of which were inhibited by
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