Triterpenoid saponins from Androsace umbellata and their anti-proliferative activities in human hepatoma cells |
| |
| Authors: | Wang Ying Zhang Dongmei Ye Wencai Yin Zhiqi Fung Kwok-Pui Zhao Shouxue Yao Xinsheng |
| |
| Institution: | Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, P R China. |
| |
| Abstract: | Two new triterpenoid saponins, along with five known ones, were isolated from the EtOH extract of the whole plants of Androsace umbellata. The structures of the new triterpenoid saponins were identified as 3- O- beta- D-xylopyranosyl-(1-->2)- beta- D-glucopyranosyl-(1-->4)- beta- D-glucopyranosyl-(1-->2)]- alpha- L-arabinopyranosyl]-3 beta-hydroxy-13 beta,28-epoxy-16-oxo-oleanan-30-al ( 1) and 3- O- beta- D-xylopyranosyl-(1-->2)- beta- D-glucopyranosyl-(1-->4)- alpha- L-arabinopyranosyl-3 beta-hydroxy-13 beta,28-epoxy-16-oxo-oleanan-30-al ( 2) on the basis of their spectral and chemical properties. All these compounds showed significant cytotoxic activities in human hepatoma cells. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
