细菌L型尿路感染及耐药性研究

目的 研究我院细菌L型尿路感染现状及耐药性。方法 对尿路感染档本采用常规与高渗同步培养，返祖后源菌应用VITEK－AMS的GP1、GN1卡进行鉴定。结果 从574分尿标本中分离出细菌L型142株，而常规培养均为阴性，阳性率提高了24.7%，其中以凝固酶阴性葡萄球菌（CNS）占首位26.8%，其次大肠埃希菌24.0％，大菌、金黄色葡萄球菌（S.A）各占18.3％、14.8％。细菌L型对青霉素呈高度耐药，头孢菌素类中度耐药，而对红霉素、氯霉素、庆大霉素、环丙沙星、克林霉素呈较低耐药性。结论 采用同步培养法可提高尿路感染阳性率，为临床尿路感染诊断及合理使用抗生素提供了重要依据。

BACTERIA L-FORM IN URETHRAL INFECTIONAND THE DRUG RESISTANCE

Aim To study the status of bacteria L-form in urethral infection and the drug resistance.Methods The routine and hyperosmotic culture were performed on the samples of urethral infection.Results 142 Strains of bacteria L-form were separated out from the negative specimens on routine culture,the positive rate was increased by 24.7%.The first was CNS (26.8%),the second was E.coli (24.0%).Enterococus D group and S.aureus were 18.3%,14.8% respectively.The drug sensitivity results showed that they were high resistant to penicilin,and low to erythromycin,gentamicin and lincomycin.ConclusionsThe method step by step culture may not only increase the positive culture rate,but also provide very important clew in the diagnosis of doubtful cases and enhance the rational administration of antibiotics.