视网膜脱离患者球后血液动力学的研究

目的观测视网膜脱离(RD)患者的球后血流动力学。方法原发性视网膜脱离(RD)患者60例, 按部分性RD25只眼;完全性RD22只眼;完全性RD伴PVR-C级以上15只眼分为三组,共62只眼。对照组38例, 共58只眼。彩色多普勒超声指导下,采用脉冲多普勒超声检测眼动脉(OA)、视网膜中央动脉(CRA)、睫状后动脉 (PCA)收缩期(PSV)、舒张期(ESV)、平均血流速度(AV)及阻力指数(RI)、搏动指数(PI)。结果三组RD患者与对照组的OA血流速度无明显差异(P>0．05);CRA、PCA的PSV、EDV、AV血流速度均减低(P<0．01);PI、RI值无显著性差异(P>0．05);且随着RD病情的加重各血流指标减低的更为明显,但组间差异无显著性(P>0．05)。结论视网膜脱离患者的血流动力学变化直接影响到视网膜的微循环状态,这为视网膜脱离的病理机制研究及药物辅助治疗提供了有力依据。

Study of haemodynamics changes of retinal detachment patients

Objective We evaluated the retrobulbar haemodynamics changes of retinal detachment patients using color Doppler ultrasound technique. Methods Color Doppler ultrasound were used to measure peak systolic velocity (PSV) ,end diastolic velocity(EDV) ,average velocity(AV) , resistance index (RI) and pulsation index (PI) of ophthalmic artery(OA),central retinal artery(CRA) and posterior ciliaries (PCA) in 60 retinal detachment patients of 62 rhegmat-ogenous eyes and also 58 normal control of 38 healthy eyes. Results The flow rates of ophthalmic artery( OA ) in retinal detachment patients had no difference compare with normal control( P >0.05). The PSV, EDV and AV of CRA and PCA in different retinal detachment patients all decreased( P <0.01 = but the PI and RI had no difference( P > 0. 05) . The degree of decrease were relatived with the damaging degree of retinal detachment, but they had no difference( P > 0.05). Conclusions The haemodynamics changes of retinal detachment have direct influence on microcirulation condition of retinal. This can provide significant foundations of retinal detachment pathological mechanism research and clinic phamic assisted therapy.