| 黄酮类化合物的潜在毒性 |
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| 引用本文： | 汪何雅,赵显峰,王茵,荫士安. 黄酮类化合物的潜在毒性[J]. 卫生研究, 2007, 36(5): 640-642 |
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| 作者姓名： | 汪何雅 赵显峰 王茵 荫士安 |
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| 作者单位： | 1. 中国疾病预防控制中心营养与食品安全所,北京,100050
2. 浙江省医学科学院保健食品研究所 |
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| 摘 要： | 黄酮类化合物广泛存在于植物类食物中,具有多种生理活性。然而,现在关于黄酮类化合物毒副作用的研究发现,某些黄酮具有遗传毒性,还可能干扰甲状腺激素的合成;异黄酮的雌激素活性可能对动物和人的生长发育带来不良影响;黄酮还可能影响营养物质的吸收、药物代谢及神经行为。本文综述了黄酮类化合物毒性方面的研究进展。
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| 关 键 词： | 黄酮 毒性 食品安全 |
| 文章编号： | 1000-8020（2007）05-0640-03 |
| 修稿时间： | 2006-09-06 |
Potential toxicities of flavonoids |
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| WANG Heya,ZHAO Xianfeng,WANG Yin,YIN Shian. Potential toxicities of flavonoids[J]. Journal of hygiene research, 2007, 36(5): 640-642 |
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| Authors: | WANG Heya ZHAO Xianfeng WANG Yin YIN Shian |
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| Affiliation: | National Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, China |
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| Abstract: | Flavonoids may be natural components came from many vegetables and fruits.A variety of heath effects of these compounds were found.However,a few safety studies indicated that certain adverse effects of these compounds could influence on human health,which could involve genotoxic/carcinogenic effects or interaction with thyroid hormone biosynthesis.Isoflavones' estrogenic activity could influence on sexual development of young animals and children.Furthermore,flavonoids could inhibit the absorption of some nutrients,interact with certain drug pharmacokinetics and affect neurobehavioral development.In this paper,the potential toxicities of flavonoids from recently published papers were reviewed. |
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| Keywords: | flavonoid toxicity food safety |
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