基于专家咨询问卷调查的更年期综合征常见证候要素

目的：运用专家咨询问卷调查的方法提取更年期综合征的常见证候要素。方法：在既往工作的基础上,制订专家咨询问卷,对全国6个中心12家三级甲等医院从事中医、中西医结合妇科临床工作且具有副主任医师及以上职称的专家进行问卷调查,在分析专家对更年期综合征常见证候要素同意程度的均数、满分比、等级和、变异系数的基础上,提取更年期综合征的常见证候要素。结果：本次调查共发放问卷100份,收回98份,回收率为98%。按照同意和完全同意的累积百分比〉50%及变异系数〈0.25的标准确定更年期综合征的常见病位类和病性类证候要素,其中病位类为肾、肝、心、脾,病性类为阴虚、精亏、阳虚、阳亢、气虚、气滞、血虚、血瘀。结论：专家咨询问卷调查能较好地收集专家的共识性意见,是确定疾病常见证候要素的有效方法;本研究所确定的更年期综合征的常见证候要素,可为进一步建立基于证候要素的证候诊断标准提供依据。

Common syndrome factors of menopausal syndrome based on questionnaire investigation among experts

Objective：To select the common syndrome factors of menopausal syndrome through questionnaire investigation among experts.Methods：Firstly,a questionnaire was constructed on the basis of our previous research,and then investigation of the experts by the questionnaire was carried out.The experts came from twelve tertiary hospitals （6 cities） in China,and engaged in clinical practice of gynecology of traditional Chinese medicine （TCM） or integrated traditional Chinese and Western medicine.The common TCM syndrome factors of menopausal syndrome were selected based on consent degree of the experts in mean value,full marks ratio,rank sum and variation coefficient.Results：One hundred sets of the questionnaires were sent out and ninety-eight sets were returned back.The callback rate was 98%.In accordance with cumulative percentage of expert agreement and complete agreement more than 50% and the coefficient variation less than 0.25,we confirmed the common TCM syndrome factors of menopause syndrome.The syndrome factors related to disease location were kidney,liver,heart,and spleen,and those related to the nature of disease were yin deficiency,deficiency of essence,yang deficiency,hyperactivity of yang,qi deficiency,qi stagnation,blood deficiency,and blood stasis.Conclusion：Expert consultation questionnaire can collect consensus opinions of experts and is effective for identifying common TCM syndrome factors of a disease.The TCM syndrome factors acquired through the study may provide the evidence for establishment of TCM syndrome diagnosis criteria for the disease in future.