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Nutritional assessments for ordinary medical care in patients with chronic liver disease
Authors:Eitaro Taniguchi  Takumi Kawaguchi  Momoka Otsuka  Yuki Uchida  Ayu Nagamatsu  Minoru Itou  Tetsuharu Oriishi  Kumiko Ishii  Minami Imanaga  Takuro Suetsugu  Jyuri Otsuyama  Ryoko Ibi  Midori Ono  Suiko Tanaka  Michio Sata
Affiliation:1. Division of Gastroenterology, Department of Medicine;2. Department of Digestive Disease Information & Research, Kurume University School of Medicine;3. Departments of Clinical Nutrition;4. Nutrition;5. Nursing, Kurume University Hospital, Kurume, Japan
Abstract:Aim: In patients with chronic liver disease who are at risk of malnutrition, simple and useful assessments for nutritional status should be established for ordinary medical care. The prognostic nutritional index (PNI) and controlling nutritional status (CONUT) are simple assessments constructed of only two or three laboratory data. We aimed to describe the potential of PNI and CONUT as a nutritional assessment tool in patients with chronic liver disease. Methods: We enrolled 165 patients, aged 18–85 years, with chronic liver disease. These patients were nutritionally assessed by PNI or CONUT, demonstrating the association with the severity of chronic liver disease or anthropometric values. Results: The value of PNI or CONUT was significantly associated with the severity of chronic liver disease (P < 0.001, respectively). In addition, the value of CONUT was significantly associated with all the anthropometric values such as body mass index (BMI, P < 0.05), mid‐arm circumference (AC, P < 0.001), mid‐arm muscle circumference (AMC, P < 0.001), and triceps skinfold thickness (TSF, P < 0.001), whereas the value of PNI was significantly associated with the values of AC (P < 0.01), AMC (P < 0.05) and TSF (P < 0.05). Approximately 80% of cirrhotic patients were assessed by PNI or CONUT to have obvious malnutrition. Conclusion: PNI and CONUT are potential tools for nutritional assessment in patients with chronic liver disease, especially for ordinary medical care, because of their simplicity.
Keywords:anthropometry  controlling nutritional status  liver cirrhosis  malnutrition  mid‐arm muscle circumference  prognostic nutritional index  triceps skinfold thickness
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