Evaluation of the antimicrobial activities of chlorhexidine gluconate,sodium hypochlorite and octenidine hydrochloride in vitro |
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| Authors: | Resmiye E. Tirali DDS PhD Haluk Bodur DDS Bilge Sipahi DDS PhD Elif Sungurtekin DDS PhD |
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| Affiliation: | 1. Department of Pediatric Dentistry, Faculty of Dentistry, University of Baskent, Ankara, Turkey;2. Department of Pediatric Dentistry, Faculty of Dentistry, University of Gazi, Ankara, Turkey;3. Department of Microbiology, School of Medicine, University of Gazi, Ankara, Turkey;4. Department of Pediatric Dentistry, Faculty of Dentistry, University of Yeditepe, Istanbul, Turkey |
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| Abstract: | The objective of this study was to compare the antimicrobial activity of sodium hypochlorite (NaOCl), chlorhexidine gluconate (CHX) and octenidine hydrochloride (OCT) in different concentrations against endodontic pathogens in vitro. Agar diffusion procedure was used to determine the antimicrobial activity of the tested materials. Enterococcus faecalis, Candida albicans and the mixture of these were used for this study. In the agar diffusion test, 5.25% NaOCl exhibited better antimicrobial effect than the other concentrations of NaOCl for all strains. All concentrations of OCT were effective against C. albicans and E. faecalis. Some 0.2% CHX was ineffective on all microorganisms. Antibacterial effectiveness of all experimental solutions decreased on the mixture of all strains. Decreasing concentrations of NaOCl resulted in significantly reduced antimicrobial effect. |
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| Keywords: | chlorhexidine gluconate irrigation solutions octenidine hydrochloride sodium hypochlorite |
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