放血联合针刺治疗急性痛风性关节炎临床研究

目的:观察放血联合针刺治疗急性痛风性关节炎(AGA)的临床疗效。方法:将符合纳入标准的78例AGA患者随机分为治疗组38例和对照组40例。治疗组采用放血联合针刺治疗,对照组口服秋水仙碱片和依托考昔片,观察周期为1周。在治疗前、治疗后1 h、4 h、1 d(疗程第2日)、3 d、7 d(全疗程结束之后次日)6个时间点进行疼痛强度自我评定以及功能障碍、红肿、拒按程度等评定;治疗前以及疗程结束后次日晨检测血尿酸(SUA)。结果:治疗后1 h,治疗组各种症状积分均降低,和治疗前比较有明显好转(P0.05),与对照组比较差异有统计学意义(P0.05);从治疗后4 h开始,对照组的疼痛较治疗前改善(P0.05),红肿、功能障碍等症状较治疗组改善不明显;疗程结束时,两组SUA水平均较治疗前下降(P0.05),但未达到正常水平。结论:放血联合针刺能迅速改善AGA红、肿、热、痛的急迫症状,在1 h即时疗效上优势明显。

Clinical Study of Bloodletting Combined with Acupuncture on Treatment of Acute Gouty Arthritis

Objective:To observe the clinical efficacy of bloodletting combined with acupuncture on the treatment of acute gouty arthritis(AGA). Methods:Seventy eight patients with AGA meeting the inclusion criteria were randomly assigned to a treatment group with 38 patients and a control group with 40 patients.The treatment group was treated with bloodletting combined with acupuncture,while the control group was given colchicine and etoricoxib tablets for oral administration. The observation period was 1 week. Pain intensity self-assessment and degrees of dysfunction,redness,and nay to be pressed were evaluated at 6 time points,before treatment,1 h,4 h,1 d(the 2 nd day of treatment),3 d,7 d(the next day after the end of the treatment) after treatment. Serum uric acid(SUA) was measured before treatment and the morning after the end of treatment. Results:At 1 h after the treatment,the scores of various symptoms in the treatment group decreased,and there was a significant improvement compared with before treatment(P<0.05). Four hours after treatment,the pain in the control group was relieved more than before treatment(P<0.05). The symptoms of redness and dysfunction were not significantly improved compared with the treatment group. At the end of the treatment,the SUA level of the two groups decreased compared with before treatment(P<0.05),but did not reach normal level. Conclusion:Bloodletting combined with acupuncture can quickly improve the acute symptoms of redness,swollen,hot and pain in AGA,and the effect is obvious in 1 h.