变应原脱敏治疗支气管哮喘疗效评价

目的 评价9种变应原对支气管哮喘患脱敏治疗的疗效与复发率。方法 选用9种变应原经皮试阳性的哮喘患行脱敏治疗。结果 本组坚持脱敏治疗一年以上的病例561例。总有效率81．64％（458／561）。临床控制率8．56％（48／561）。脱敏治疗小于2年，停药后复发率高达79．39％（208／262），脱敏治疗大于2年和3年停药后复发率分别为47．09％（81／172）和22．33％（23／103）．三组间比较差异显（P＜0．001）。结论：脱敏对过敏原明确的哮喘患临床疗效显，复发率和治疗时间呈相关。

The effective accessment of desensization by using allergens on patients with asthma.

Objective To access the efficacy and repalse rate of desensitization in patients with asthma by using allergens.Methods Nine kinds of allergens with positive skin test were chosen to desensitize patients with asthma.Results Among 561 patients who persisted in desensitizing beyond one year,total effective rate and clinic control rate were 81.64% and 8.56% respectively.The repasle rates decreased clearly onestime:79.39%,47.09% and 22.33% for the patients desensitized overn one year,2 years and 3 years,respectively.Conclusions The efficacy of desensitization in patients with asthma using definite allergens is clear.The relapse rate is associated with the length ot time in treatment.