Subtypes of HBsAg in Eastern and South-Eastern Europe |
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| Authors: | K Madali&#;ski P V Holland Z Moraczewska B Kalinowska and H J Alter |
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| Institution: | Department of immunopathology, State Institute of Hygiene, Warsaw;Blood Bank Department. Clinical Center, NIH, Rethesda, Md., and Cepartnient of Serology, Institute of Haernatology, Warsaw |
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| Abstract: | Abstract. A total of 481 serum samples was collected from asymptomatic carriers of H B,Ag as well as some patients with acute and chronic hepatitis, type B. The sera were obtained mainly from blood banks in the following countries: Poland, Hungary, Romania, Bulgaria, Yugoslavia, and the European part of the Soviet Union. Asymptomatic carriers of HBsAg from Poland and Hungary showed a preponderance of adw subtype over uyw subtype (Poland -80.7% adw , Hungary -72.2% adw). Carriers from the remaining countries showed the reverse situation: Bulgaria -71.5% ayw , Yugoslavia -79.0% ayw , Romania -82.8% ayw , Soviet Union -87.5% ayw. No individuals were found among these indigenous populations to have the adr or ayr subtypes but two carriers appeared to have the unusual subtype adyw. |
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