南宁市1989～1999年不同民族儿童1型糖尿病发病率的流行病学调查

目的调查南宁市儿童1型糖尿病( IDDM)的发病率. 方法依据 WHO DiaMond计划,采用捕获-再捕获方法,对1997～ 1999年间 15岁以内新诊断为 1型糖尿病的儿童进行回顾性登记.结果 1997～ 1999年间南宁市 15岁以内儿童发生 IDDM 19例,年平均发病率男性为0.89/10万,女性 0.86/10万,总发病率为 0.75/10万.城市为 1.71/10万,乡村为0.43/10万,汉族为 1.38/10万,壮族为 0.51/10万.南宁城市与乡村间 IDDM发病率有显著性差异(P< 0.001),汉族与壮族间有明显差异( P< 0.05). 结论南宁市 1997～ 1999年儿童IDDM发病率有上升的趋势,遗传因素与 IDDM发病率存在密切关系.

The incidence of insulin-dependent diabetes mellitus in children of the different ethnic groups in Nanning during 1989-1999

AIM: To investigate the incidence of insulin-dependent diabetes mellitus ( IDDM) in children of Nanning city. METHODS: Based on WHO DiaMond Project, during 1997- 1999, all the children under 15 years who were diagnosed to suffer from IDDM were retrospectively registered by the "catching-recatching" method. RESULTS: The results showed that the yearly incidence of IDDM was 0.89/100, 000 in boys, 0.60/100 000 in girls, with a total yearly incidence of 0.75/100 000 in children under 15 years old. Among the cases, the IDDM incidence in urban areas was 1.71/100 000 and 0.43/100 000 in rural areas. Also, among the cases, the incidence of IDDM was 1.38/100 000 in Han nationality and 0.51/100 000 in Zhuang nationality. There was significant difference between IDDM incidence of the urban areas and the rural areas(P< 0.001), between Han and Zhuang nationalities (P< 0.05). CONCLUSION: The incidence of IDDM tended to increase in children in Nanning city during 1997- 1999,which is closely related with genetic factors.