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蜘蛛香的化学成分研究
引用本文:许婧,刘翠周,桂丽萍,郭萍,郭远强. 蜘蛛香的化学成分研究[J]. 药物评价研究, 2010, 0(2): 132-134
作者姓名:许婧  刘翠周  桂丽萍  郭萍  郭远强
作者单位:南开大学,天津300071
基金项目:国家自然科学基金青年基金项目(30801432)
摘    要:目的:研究蜘蛛香Valeriana jatamansi的化学成分。方法:通过各种色谱手段(Silica gel、ODS、HPLC)对蜘蛛香甲醇提取物进行分离纯化,通过^1H—NMR、^13C-NMR等波谱技术确定化合物的结构。结果:分离并鉴定了4个含氯元素的环烯醚萜类化合物,分别为rupesin B(1)、chlorovaltrate(2)、volvaltrates B(3)、1,5-dihydroxy-3.8-epoxyvalechlorine A(4)。结论:化合物1~3为首次从植物蜘蛛香中分离得到。

关 键 词:蜘蛛香  化学成分  环烯醚萜

Studies on chemical constituents of Valerianajatamansi
XU Jing,LIU Cui-zhou,GUI Li-ping,GUO Ping,GUO Yuan-qiang. Studies on chemical constituents of Valerianajatamansi[J]. Drug Evaluation Research, 2010, 0(2): 132-134
Authors:XU Jing  LIU Cui-zhou  GUI Li-ping  GUO Ping  GUO Yuan-qiang
Affiliation:( Nankai University, Tianjin 300071, China)
Abstract:Objective: To investigate the chemical constituents from the seeds of Valerianajatamansi. Methods: The compounds were isolated by chromatography and identified on the basis of physico-chemical constants and spectral analysis. Results: Four iridoid compounds were isolated and their structures were identified as rupesi B (1), chlorovaltrate (2), volvaltrates B (3), 1, 5-dihydroxy-3, 8-epoxyvalechlorine A (4). Conelusion: Compounds 1-3 are isolated from this plant for the first time.
Keywords:Valerianajatamansi Jones  chemical consitutents  iridoids
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