| 胰岛素及其类似物的研究进展 |
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| 引用本文： | 张春云,蔡永明,张骏,王海荣,张宗鹏. 胰岛素及其类似物的研究进展[J]. 药物评价研究, 2010, 0(6): 436-441 |
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| 作者姓名： | 张春云 蔡永明 张骏 王海荣 张宗鹏 |
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| 作者单位： | [1]天津中医药大学,天津300193 [2]天津药物研究院,天津300193 [3]天津医科大学,天津300193 |
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| 基金项目： | 国家科技支撑计划项目（2007BA141B04）,“重大新药创制”科技重大专项（2008ZX09305-005）,天津创新药物安全评价技术平台建设 |
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| 摘 要： | 自胰岛素首次用于治疗糖尿病以来,随着对糖尿病病理生理和发病机制认识的深入,胰岛素的应用越来越广泛。综述近年来相关文献中有关胰岛素及其类似物制剂的分类、给药途径、体内吸收代谢、临床应用和不良反应等方面内容,为进一步研究、开发和合理利用胰岛素及其类似物提供参考。
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| 关 键 词： | 胰岛素 胰岛素类似物 临床应用 不良反应 糖尿病 |
Research progress of insulin and its analogues |
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| Zhang Chun-yun,Cai Yong-ming,Zhang Jun,Wang Hai-rong,Zhang Zong-peng. Research progress of insulin and its analogues[J]. Drug Evaluation Research, 2010, 0(6): 436-441 |
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| Authors: | Zhang Chun-yun Cai Yong-ming Zhang Jun Wang Hai-rong Zhang Zong-peng |
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| Affiliation: | 1 Tianjin University of Tradtional Chinese Medicine, Tianjin 300193, China ;2 Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China ;3 Tianjin Medical University, Tianjin 300193, China) |
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| Abstract: | Since the first time insulin used in the treatment of diabetes, and with the development ofpathophysiology and pathogenesis in diabetes, insulin has been gaining a widely usage. For the future research, development and rational utilization of insulin, this paper reviews recent literature relating to classification, administrations, absorption, metabolism, clinical applications, adverse reactions of insulin and its analogues. |
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| Keywords: | insulin insulin analogues clinical application adverse effect diabetes |
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