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鼠类流行性出血热病毒携带率影响因素的研究
引用本文:杨经华,张荻,夏祝辉,刘建珍,何尚浦.鼠类流行性出血热病毒携带率影响因素的研究[J].华中科技大学学报(医学版),1990(5).
作者姓名:杨经华  张荻  夏祝辉  刘建珍  何尚浦
作者单位:同济医科大学实验动物中心 (杨经华),同济医科大学公共卫生学院流行病学教研室 (张荻,夏祝辉),同济医科大学保健科 (刘建珍),同济医科大学公共卫生学院流行病学教研室(何尚浦)
摘    要:本文报道1987年9月,在某校大面积灭鼠的同时,应用间接免疫荧光法进行了鼠类流行性出血热(EHFV)病毒携带状况检查,结果查鼠肺219份,EHFV抗原阳性20份(9.1%),研究认为:用5/万敌鼠钠盐灭鼠对鼠肺检出EHFV抗原无影响;黄胸鼠、褐家鼠及其黑变型均可携带EHFV;其鼠密度与带病率呈正相关关系;雌鼠及成年鼠带病毒率明显高于雄鼠和非成年鼠。

关 键 词:出血热病毒  流行性  病毒携带率  鼠密度  间接免疫荧光法

A Preliminary Study of Some Factors Influencing the Epidemic Hemorrhagic Fever Virus Carrier Rate in Mus
Yang Jinghua,Zhang Di,Xia Zhuhui,Liu Jianzhen,He Shangpu Medical Experimental Animal Center,Tongji Medical University,Wuhan.A Preliminary Study of Some Factors Influencing the Epidemic Hemorrhagic Fever Virus Carrier Rate in Mus[J].Journal of Huazhong University of Science and Technology(Health Sciences),1990(5).
Authors:Yang Jinghua  Zhang Di  Xia Zhuhui  Liu Jianzhen  He Shangpu Medical Experimental Animal Center  Tongji Medical University  Wuhan
Institution:Yang Jinghua,Zhang Di,Xia Zhuhui,Liu Jianzhen,He Shangpu Medical Experimental Animal Center,Tongji Medical University,Wuhan Department of Epidemiology,Faculty of Public Health Health Care Department
Abstract:219 murine lungs were examined to detect Epidemic HemorrhagicFever Virus (EHFV) carrier rate in mus by indirect immunofluorescence technique.These samples were taken from a university where deratization was conducted on a large scale in Sep 1987.It was found that 20 out of all the examined samples showed the positive reaction against antigen of EHFV (9.1%).These findings indicated that no effects would be observed in the check-up EHFV antigen in mus by application of 5/10 000 diphacin.Rattus flavipectus,Rattus norvegicus and black variety of Rattus norvegicus were EHFV carriers.There was a positive correlation between rat density and virus carrier rate,and the virus carrier rate of female rats and adult rats was remarkably higher than that of the male rats and nonadult rats
Keywords:hemorrhagic fever virus  virus carrier rate  rat density  indirect immuno-fluorescence
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