Abstract: | In experimentsin vitro after preliminary incubation of fibrinogen with terrilytin clot formation was retarded and subsequent lysis accelerated. Terrilytinin vitro lengthened the recalcification time, reduced thromboplastic activity and fibrinase activity and, at the same time, increased the fibrinolytic activity of blood plasma. In experiments on dogs roentgenovasography revealed considerable thrombolytic activity of terrilytin when injected intravenously into animals with experimental thrombosis of the femoral veins.Pathophysiological Laboratory, Institute of Human Morphology, Academy of Medical Sciences of the USSR. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 8, pp. 936–937, August, 1976. |