多中心型Castleman病CT表现(附1例报告与文献复习)

目的　评价多中心型Castleman病 (CD)的CT表现。方法　回顾性分析 1例经淋巴结活检证实的多中心型CD患者的胸、腹部CT表现 ,并作文献复习。结果　患者具有全身症状 ,多克隆性高丙球蛋白血症 ,全身浅深淋巴结广泛肿大并增强扫描轻度强化 (约 2 0HU) ,肺实质出现特异性浸润 ,包括小叶中心性分布的弥漫小结节、磨玻璃灶、薄壁气囊、支气管血管束和小叶间隔增厚 ,与文献高度一致。结论　多中心型CD具有明显的临床全身症状、全身广泛的淋巴结肿大并轻中度强化 ,侵犯肺实质时病变有一定特点 ,典型表现可提示本病。

Multicentric Castleman Disease: CT Findings(A Report of one Case and a Review of the Literature)

Objective To evaluate the CT findings of multicentric Castleman disease(CD).Methods The CT findings of thorax and abdomen in a patient with multicentric CD biopsy-proved were retrospectively analyzed, and a literature review was conducted.Results The patient had systemic symptoms, polyclonal hypergammaglobulinemia, extensive lymph node enlargement and mild enhancement, and specific pulmonary infiltration. The lung lesions on thin-section CT were showed poorly-defined centrilobular nodules, ground-glass attenuation, thin-walled cysts, thickening of the bronchovascular bundles, and interlobular septal thickening. The above were highly coincident with that in the literatures.Conclusion Multicentric CD is characterized by the presence of systemic symptoms, extensive lymph node enlargement and mild enhancement, and specific pulmonary lesions when infiltrated. Typical manifestation might suggest multicentric CD.