| C-erbB-2在胃癌及贲门癌组织中表达的临床研究 |
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| 引用本文： | 凌斌勋,陈环球,徐新宇,周兆飞,陆建伟. C-erbB-2在胃癌及贲门癌组织中表达的临床研究[J]. 实用临床医药杂志, 2008, 12(9): 37-39 |
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| 作者姓名： | 凌斌勋 陈环球 徐新宇 周兆飞 陆建伟 |
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| 作者单位： | 江苏省肿瘤医院内科,江苏,南京,210009;江苏省肿瘤医院普外科,江苏,南京,210009;江苏省肿瘤医院病理科,江苏,南京,210009 |
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| 基金项目： | 江苏省人事厅六大人才高峰项目，江苏省社会发展基金 |
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| 摘 要： | 目的用免疫组化法对209例胃癌及贲门癌组织进行C-erbB-2表达的研究。结果209例胃癌及贲门癌组织中C-erbB-2表达阳性率为6.73%(14/209),其表达与年龄、病变部位、病理类型、分化程度等密切相关(P<0.05).而与性别、肿瘤浸润深度、淋巴结转移阳性、有无远处转移、临床分期等均无明显关系。结论C-erbB-2的表达与胃癌及贲门癌的生物学行为有一定的相关性。
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| 关 键 词： | 胃癌 贲门癌 C-erbB-2 免疫组化 |
A Clinical Study of C-erbB-2 Expression in Gastric and Cardiac Cancer |
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| LING Bin-xun,CHEN Huan-qiu,XU Xin-yu,ZOU Zao-fei,LU Jian-wei. A Clinical Study of C-erbB-2 Expression in Gastric and Cardiac Cancer[J]. Journal of Clinical Medicine in Practice, 2008, 12(9): 37-39 |
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| Authors: | LING Bin-xun CHEN Huan-qiu XU Xin-yu ZOU Zao-fei LU Jian-wei |
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| Abstract: | Objective To study the expression of C-erbB-2 in 209 cases of gastric and car- diac cancer by immunohistochemistry.Results The positive expression of C-erbB-2 was detected in 14 of 209 gastric and cardiac cancer samples (6.73%) and related to age,site of tumor,pathology type and degree of differentiation (P<0.05).No correlation existed between the expression in neo- plastic tissues with sex,the depth of invasion,lymph node metastasis,distant metastasis and clini- cal stage.Conclusion The expression of C-erbB-2 has a closely relationship with biological behavior of human gastric and cardiac cancer. |
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| Keywords: | gastric cancer cardiac cancer C-erbB-2 immunohistochemistry |
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