Evaluation of oxygen uptake adjusted by skeletal muscle mass in
cardiovascular disease patients with type 2 diabetes |
| |
| Authors: | Nana Takao Junji Iwasaka Satoshi Kurose Takumi Miyauchi Astuko Tamanoi Ryota Tsuyuguchi Aya Fujii Hiromi Tsutsumi Yutaka Kimura |
| |
| Institution: | 1) Department of Health Science, Graduate School of Medicine, Kansai Medical University: 2-5-1 Shinmachi, Hirakata 573-1010, Japan;2) Health Science Center, Kansai Medical University Hospital, Japan;3) Department of Medicine II, Kansai Medical University, Japan;4) Department of Health Science, Kansai Medical University, Japan |
| |
| Abstract: | Purpose] We aimed to evaluate oxygen uptake adjusted by total skeletal muscle mass in patients with cardiovascular disease with or without type 2 diabetes mellitus. Participants and Methods] The participants included 54 males ≥50 years of age without heart failure who underwent cardiopulmonary exercise testing during cardiac rehabilitation. We divided the participants into two groups: patients with type 2 diabetes mellitus (DM group) and patients without type 2 diabetes mellitus (NDM group). Results] We found no significant differences in age, weight, fat mass, or skeletal muscle mass between the groups. There were also no differences in cardiac function, body composition, and heart rate response. The DM group showed significantly lower peak oxygen uptake values adjusted by skeletal muscle mass, despite the absence of significant differences in skeletal muscle mass. A significant positive correlation was found between peak oxygen uptake and age, weight, and skeletal muscle mass. Stepwise regression analysis revealed that age, skeletal muscle mass, and medical history of diabetes were independent predictors of absolute peak oxygen uptake. Conclusion] Peak oxygen uptake adjusted by skeletal muscle mass in patients with cardiovascular disease and type 2 diabetes mellitus is lower than that in those without type 2 diabetes mellitus.Key words: Cardiopulmonary exercise testing, Peak oxygen uptake, Skeletal muscle mass |
| |
| Keywords: | |
|
|
