关于剖宫产预防性应用抗生素问题探讨

总结我院１９９６年１０月至１９９７年２月共４个月的剖宫产病例１６３例，预防性应用抗生素的情况。对其中１０６例术前已破膜的病人选用青霉素Ｇ加０．５％甲硝唑静滴三天，或头孢西丁静推一次，剖宫产术后感染率分别为１１％、２０％，两组间无显著性差异（Ｐ〉０．０５）。对５７例术前未破膜的病人预防性应用青霉素Ｇ加０．５％甲硝唑静滴三天，与维生素ｃ静滴组对照，剖宫产术后感染率为９％、８％，亦无显著性差异（Ｐ〉０．

Preventative application of antibiotics before cesarean section

163 patients received cesarean sections in this hospital from October, 1996 to December, 1997. 106 patients with premature rupture of membranes (PROM) were given either penicillin G and 0.5% metronidazole by intrsvenous infusion for three days or cefoitin by intravenous injection once before operation, and no statistical difference was found between the two groups (11%and 20% infection rate P>0.05). 32 patients with no premature rupture of membranes were also given penicillin G and 0.5% metronidazole before opefation and 25 patients were given vitamin C as control, and no difference was found (9.4% and 8% infection ratep> 0.05). This study demonstrated that penicillin G and 0.5% metronidazole and cefoitin were effective for preventing infection in PROM, and that antibiotics were not necessary for elective cesarean section.