手术对甲状腺机能亢进患者T_3、T_4、TGA、TMA、TSH及皮质醇的影响

对30例甲状腺机能亢进患者手术前后血清甲状腺激素(T_3、T_4)、促甲状腺激素(TSH)、甲状腺球蛋白抗体(TGA)、甲状腺微粒体抗体(TMA)及皮质醇进行测定。结果:行甲状腺大部切除术后患者血清T_3、T_4、TMA、TGA在短期内迅速下降,皮质醇则在原低下的水平上更趋下降,而TSH的变化不大。甲状腺大部切除术对非甲状腺机能亢进患者的上述指标影响不大。因此,此类激素和抗体的测定对判断手术效果及预防甲状腺机能亢进危象的发生具有一定的临床意义。

TRIIODOTHYRONINE, THYROXINE, THYROID STIMULATING HORMONE, THYROGLOBULIN ANTIBODY, THYROMICROSOME ANTIBODY AND HYDROCORTISONE IN PATIENTS WITH HY-PERTHYROIDISM AFTER SUBTOTAL THYROIDECTOMY

Thirty patients with heperthyroidism were investigated for triiodothyronine(T3),thyrox-tne(T4), thyroid stimulating hormone (TSH),thyromicrosome antibody(TMA),thyroglobulin antibody (TGA)and hydrocortisone before and after operation. The levels of serum T3, T4,TGA,TMA were markedly decreased after operation,and the level of hydrocortisone farther decreased from the preopera-tive low level. But only a little decrease in TSH level was found as compared with that before operation. The assay of these hormones and antibodies has very important clinical significance for judgement of the effect of operation and prevention of crisis of hypertEyroidism.